tailieunhanh - Chinese red yeast rice (Monascus purpureus) for primary hyperlipidemia: a meta-analysis of randomized controlled trials

The neuromatrix, which is genetically determined and modified by sensory, emotional, cog- nitive, and memory experience, is the primary mechanism that generates the neural pattern that produces pain. Its output pattern is determined by multiple influences, of which the somatic sensory input is only a part, that converge on the neuromatrix. Acute pain problems evoked by brief noxious inputs have been carefully investigated by neuroscien- tists, and their sensory transmission mechanisms are generally well understood. In contrast, chronic pain syndromes that are often characterized by severe pain associated with less obvious injury or pathology involve more complex systems in the central nervous system. | Chinese Medicine BioMed Central Review Open Access Chinese red yeast rice Monascus purpureus for primary hyperlipidemia a meta-analysis of randomized controlled trials Jianping Liu 1 4 Jing Zhang2 Yi Shi3 Sameline Grimsgaard1 Terje Alraek1 and Vinjar Fonnebo1 Address 1National Research Centre in Complementary and Alternative Medicine NAFKAM University of Tromso Tromso N-9037 Norway 2Evidence-Based Medicine Centre in Traditional Chinese Medicine Shanghai University of Traditional Chinese Medicine Cai Lun Lu 1200 Pudong Shanghai 201203 China 3The Institute of Traditional Chinese Medicine Literature Shanghai University of Traditional Chinese Medicine Cai Lun Lu 1200 Pudong Shanghai 201203 China and 4Evidence-Based Chinese Medicine Research Centre Beijing University of Chinese Medicine Beijing 100029 China Email Jianping Liu - Jing Zhang - n@ Yi Shi - a@ Sameline Grimsgaard - b@ Terje Alraek - c@ Vinjar Fonnebo - Corresponding author Published 23 November 2006 Chinese Medicine 2006 1 4 doi l749-8546-l-4 Received 28 February 2006 Accepted 23 November 2006 This article is available from http content l l 4 2006 Liu et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Extracts of Chinese red yeast rice RYR a traditional dietary seasoning of Monascus purpureus contains several active ingredients including lovastatin and several trials of its possible lipid-lowering effects have been conducted. This meta-analysis assesses the effectiveness and safety of RYR preparations on lipid modification in primary hyperlipidemia. We included randomized controlled trials testing RYR preparation compared .