tailieunhanh - Báo cáo sinh học: "India's 'gold mine' of ancestral bacilli and the looming TB-HIV pandemic"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học Clinical Microbiology đề tài: India's 'gold mine' of ancestral bacilli and the looming TB-HIV pandemic. | BioMed Central Annals of Clinical Microbiology and Antimicrobials Open Access Editorial India s gold mine of ancestral bacilli and the looming TB-HIV pandemic Niyaz Ahmed 1 and Hakan Leblebicioglu2 Address Pathogen Evolution Group Centre for DNA Fingerprinting and Diagnostics CDFD Hyderabad India and 2Department of Infectious Diseases and Clinical Microbiology Ondokuz Mayis University Medical School Samsun Turkey Email Niyaz Ahmed - Hakan Leblebicioglu - hakanomu@ Corresponding author Published 22 December 2006 Received 19 December 2006 . __J - z r - i AHI r I Accepted 22 December 2006 Annals of Clinical Microbiology and Antimicrobials 2006 5 31 doi l476-07ll-5-3l This article is available from http content 5 l 3 l 2006 Ahmed and Leblebicioglu licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Editorial It s almost a decade since the whole genome sequence of the tubercle bacillus M. tuberculosis was completed. The genome sequence of tuberculosis TB bacteria has opened various new avenues for studying biology of TB as well as heralded major funding possibilities for researchers worldwide. However it is pathetic to realize that we do not have ready a promising new drug target a perfect vaccine candidate or a gold standard diagnostic marker as yet for this dreaded pestilence. Countries like India are worst sufferers of such a disappointingly delayed fruit of post-genomic TB research and technology. Nonetheless significant benefits arising in terms of exploratory genomics have helped the clinical cause of tracking and analyzing the strains of epidemic potential. Gutierrez and colleagues 1 in a recently reported multicentric research based on genotyping of TB .