tailieunhanh - Báo cáo y học: " Autonomic Dysfunction Presenting as Postural Orthostatic Tachycardia Syndrome in Patients with Multiple Sclerosis"

Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Autonomic Dysfunction Presenting as Postural Orthostatic Tachycardia Syndrome in Patients with Multiple Sclerosis. | Int. J. Med. Sci. 2010 7 62 International Journal of Medical Sciences 2010 7 2 62-67 Ivyspring International Publisher. All rights reserved Research Paper Autonomic Dysfunction Presenting as Postural Orthostatic Tachycardia Syndrome in Patients with Multiple Sclerosis Khalil Kanjwal Beverly Karabin Yousuf Kanjwal Blair P Grubb H Department of Medicine Division of Cardiology Section of Electrophysiology The University of Toledo Toledo OH 43614 USA. H Corresponding author Blair P Grubb MD Director Electrophysiology Services Division of Cardiology Department of Medicine Health Sciences Campus University of Toledo Medical Center Mail Stop 1118 3000 Arlington Ave. Toledo OH 43614. USA. Phone 419-3833778 Fax 419-383-3041. Received Accepted Published Abstract Background Autonomic dysfunction is common in patients suffering from multiple sclerosis MS and orthostatic dizziness occurs in almost 50 of these patients. However there have been no reports on postural orthostatic tachycardia syndrome POTS in patients suffering from MS. Methods The patients were included for analysis in this study if they had POTS with either a prior history of MS or having developed MS while being followed for POTS. Postural orthostatic tachycardia POTS is defined as symptoms of orthostatic intolerance 6months accompanied by a heart rate increase of at least 30 beats min or a rate that exceeds 120 beats min that occurs in the first 10 minutes of upright posture or head up tilt test HUTT occurring in the absence of other chronic debilitating disorders. We identified nine patients with POTS who were suffering from MS as well. Each of these patients had been referred from various other centers for second opinions. Results The mean age at the time of diagnosis of POTS was 49 9 years and eight of the 9 patients were women. Five patients 55 had hyperlipidemia 3 33 migraine and 2 22 patients had coronary artery disease and diabetes each. Fatigue and palpitations on .