tailieunhanh - báo cáo hóa học:" An application of principal component analysis to the clavicle and clavicle fixation devices"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : An application of principal component analysis to the clavicle and clavicle fixation devices | Daruwalla et al. Journal of Orthopaedic Surgery and Research 2010 5 21 http content 5 1 21 JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH RESEARCH ARTICLE Open Access An application of principal component analysis to the clavicle and clavicle fixation devices 1 2 2 2 1 Zubin J Daruwalla Patrick Courtis Clare Fitzpatrick David Fitzpatrick Hannan Mullett Abstract Background Principal component analysis PCA enables the building of statistical shape models of bones and joints. This has been used in conjunction with computer assisted surgery in the past. However PCA of the clavicle has not been performed. Using PCA we present a novel method that examines the major modes of size and three-dimensional shape variation in male and female clavicles and suggests a method of grouping the clavicle into size and shape categories. Materials and methods Twenty-one high-resolution computerized tomography scans of the clavicle were reconstructed and analyzed using a specifically developed statistical software package. After performing statistical shape analysis PCA was applied to study the factors that account for anatomical variation. Results The first principal component representing size accounted for percent of anatomical variation. The addition of a further three principal components accounted for almost 87 percent. Using statistical shape analysis clavicles in males have a greater lateral depth and are longer wider and thicker than in females. However the sternal angle in females is larger than in males. PCA confirmed these differences between genders but also noted that men exhibit greater variance and classified clavicles into five morphological groups. Discussion And Conclusions This unique approach is the first that standardizes a clavicular orientation. It provides information that is useful to both the biomedical engineer and clinician. Other applications include implant design with regard to modifying current or designing future clavicle fixation .