tailieunhanh - báo cáo hóa học:" Maternal plasma viral load and neutralizing/enhancing antibodies in vertical transmission of HIV: A non-randomized prospective study"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học đề tài : Maternal plasma viral load and neutralizing/enhancing antibodies in vertical transmission of HIV: A non-randomized prospective study | BioMed Central Virology Journal Research Open Access Maternal plasma viral load and neutralizing enhancing antibodies in vertical transmission of HIV A non-randomized prospective study Paul Kamara1 Loyda Melendez-Guerrero2 Miguel Arroyo3 Heidi Weiss4 and Pauline Jolly 1 Address Department of Epidemiology School of Public Health University of Alabama at Birmingham 1665 University Blvd. Ryals Building Room 217 Birmingham AL 35294-0022 USA 2Department of Microbiology and Medical Zoology University of Puerto Rico Medical Sciences Campus School of Medicine San Juan Puerto Rico 3US Military HIV Research Program Walter Reed Army Institute of Research Division of Retrovirology Silver Spring MD 20910 USA and 4Breast Center Baylor College of Medicine One Baylor Plaza MS BCM 600 335A Houston TX 77030 USA Email Paul Kamara - PaulKamara@ Loyda Melendez-Guerrero - lmelendez@ Miguel Arroyo - marroyo@ Heidi Weiss - hweiss@ Pauline Jolly - jollyp@ Corresponding author Published 24 February 2005 Received 05 October 2004 Accepted 24 February 2005 Virology Journal 2005 2 15 doi l 743-422X-2-15 This article is available from http content 2 1 15 2005 Kamara et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background We examined the association and interaction between maternal viral load and antibodies in vertical transmission of HIV in a non-randomized prospective study of 43 HIV-1 infected pregnant women who attended the San Juan City Hospital Puerto Rico and their 45 newborn infants. The women and infants received antiretroviral therapy. Methods A nested PCR assay of the HIV-1 envelope V3 region and infant PBMC culture were performed to .