tailieunhanh - báo cáo hóa học:" Optical Nerve Detection by Diffuse Reflectance Spectroscopy for Feedback Controlled Oral and Maxillofacial Laser Surgery"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học đề tài : Optical Nerve Detection by Diffuse Reflectance Spectroscopy for Feedback Controlled Oral and Maxillofacial Laser Surgery | Stelzle et al. Journal of Translational Medicine 2011 9 20 http content 9 1 20 TRANSLATIONAL MEDICINE RESEARCH Open Access Optical Nerve Detection by Diffuse Reflectance Spectroscopy for Feedback Controlled Oral and Maxillofacial Laser Surgery PlinrÌTỉn cfoI 71o 1A 7H r 7m n4 Warner AHIor5 T n ormiamo-íTlorl 2 Alov nHro Pimi ir diL 4 rioiidn Steizie Aziidi Zam vveinei Adiei Kdtjd Idngeimdnn Geik Aiexdndie Doupiik Emeka Nkenke1 Michdei Schmidt2 3 Abstract Background Ldsei suigeiy idcks hdptic feedbdck which is dccompdnied by the iisk of idtiogenic neive ddmdge. It wds the dim of this study to investigdte diffuse iefiectdnce spectroscopy foi tissue diffeientidtion ds the bdse of d feedbdck contioi system to enhdnce neive preservdtion in oidi dnd mdxiiiofdcidi idsei suigeiy. Methods Diffuse iefiectdnce spectid of neive tissue sdiivdiy gidnd dnd bone 8640 spectid of the mid-fdcidi iegion of ex vivo domestic pigs weie dcquiied in the wdveiength idnge of 350-650 nm. Tissue diffeientidtion wds peifoimed using piincipdi component PC dndiysis foiiowed by iinedi disciimindnt dndiysis LDA . Specificity dnd sensitivity weie cdicuidted using ieceivei operating chdidcteiistic ROC dndiysis dnd the died undei cuive AUC . Results Five PCs weie found to be ddequdte foi tissue diffeientidtion with diffuse iefiectdnce spectid using LDA. Neive tissue couid be differed fiom bone ds weii ds fiom sdiivdiy gidnd with AUC iesuits of giedtei thdn 88 sensitivity of giedtei thdn 83 dnd specificity in excess of 78 . Conclusions Diffuse iefiectdnce spectroscopy is dn ddequdte technique foi neive identificdtion in the vicinity of bone dnd sdiivdiy gidnd. The iesuits set the bdsis foi d feedbdck system to pievent idtiogenic neive ddmdge when peifoiming oidi dnd mdxiiiofdcidi idsei suigeiy. Introduction Laser surgery provides several advantages. Lasers allow cutting biological tissue with high precision and minimal trauma. Furthermore the ability to work remotely .