tailieunhanh - Báo cáo y học: "Theta, alpha and beta burst transcranial magnetic stimulation: brain modulation in tinnitus"

Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Theta, alpha and beta burst transcranial magnetic stimulation: brain modulation in tinnitus. | Int. J. Med. Sci. 2007 4 237 Research Paper International Journal of Medical Sciences ISSN 1449-1907 2007 4 5 237-241 Ivyspring International Publisher. All rights reserved Theta alpha and beta burst transcranial magnetic stimulation brain modulation in tinnitus Dirk De Ridder 1 Elsa van der Loo 1 Karolien Van der Kelen 1 Tomas Menovsky 1 Paul van de Heyning 1 Aage Moller 2 1. Dept of Neurosurgery and ENT University Hospital Antwerp Belgium 2. School of Behavioral and Brain Science University of Texas at Dallas Dallas USA Correspondence to Dirk De Ridder Dept of Neurosurgery University Hospital Antwerp Wilrijkstraat 10 2650 Edegem Belgium. Tel 32 3 8213336 Fax 32 3 8252428 Received Accepted Published Introduction Some forms of tinnitus are considered to be auditory phantom phenomena related to reorganization and hyperactivity of the auditory central nervous system. Repetitive transcranial magnetic stimulation rTMS is a non-invasive tool capable of modulating human brain activity using single pulse or burst stimuli. Burst rTMS has only been performed in the theta range and has not been used clinically. The authors analyze whether burst TMS at theta 5 Hz alpha 10 Hz and beta 20 Hz frequencies can temporarily suppress narrow band noise white noise tinnitus Which has been demonstrated to be intractable to tonic stimulation. Methods rTMS is performed both in tonic and burst mode in 46 patients contralateral to the tinnitus side at 5 10 and 20 Hz. Fourteen placebo negative rTMS responders are further analyzed. Results In 5 patients maximal tinnitus suppression is obtained with theta in 2 with alpha and in 7 with beta burst stimulation. Burst rTMS suppresses narrow band white tinnitus much better than tonic rTMS f 13 p .000. Women experience greater suppression of their tinnitus with burst stimulation than men f 12 p .05. Furthermore left sided tinnitus is perceived as more distressing