tailieunhanh - Báo cáo y học: "Ocular Manifestations of Rickettsiosis: 1. Mediterranean Spotted Fever: laboratory analysis and case reports"

Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Ocular Manifestations of Rickettsiosis: 1. Mediterranean Spotted Fever: laboratory analysis and case reports. | Int. J. Med. Sci. 2009 6 126 Short Communication International Journal of Medical Sciences 2009 6 3 126-127 Ivyspring International Publisher. All rights reserved Ocular Manifestations of Rickettsiosis 1. Mediterranean Spotted Fever laboratory analysis and case reports Antonio Pinna Institute of Ophthalmology University of Sassari Sassari Italy Published Introduction Rickettsiae are short pleomorphic but usually rod-shaped or coccobacillary Gram-negative bacteria that grow strictly in eukaryotic cells obligate intracellular parasites . They have the ability to multiply in one or more arthropods and to exist in natural reservoirs of one or several warm-blooded animal hosts including humans. Rickettsiae are divided into 5 groups 1 Spotted fever group including R. rickettsii R. conorii and R. akari 2 Typhus group including R. prowazekii and R. typhi 3 Scrub typhus R. tsutsuga-mushi 4 Q fever Coxiella burnetii 5 Neorickettsio-sis. In the Spotted fever group R. rickettsii is the etiological agent of Rocky Mountain spotted fever transmitted by the bite of a tick whereas R. akari is the etiological agent of rickettsialpox transmitted by the bite of a mite. Rickettsia conorii the most widespread rickettsia of the spotted fever group is the etiological agent of Mediterranean spotted fever MSF in humans. The brown dog tick Rhipicephalus sanguineous is the prevalent vector. The disease is normally transmitted by tick bite but it may also be acquired through the skin or eye when the ticks are crushed. The disease is endemic during the spring and summer in most of the regions bordering on the Mediterranean and Black seas in Kenya and other parts of central Africa South Africa and certain parts of India. MSF varies in severity but is seldom fatal. The incubation period is 5-7 days and the onset is sudden in about 50 of cases. The duration of disease is 7-14 days. The clinical signs and symptoms include fever up to 40 C headache chills myalgias arthralgias malaise and

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