tailieunhanh - Báo cáo y học: Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects"

Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects. | Int. J. Med. Sci. 2009 6 65 International Journal of Medical Sciences 2009 6 2 65-71 Ivyspring International Publisher. All rights reserved Research Paper Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects Andrea BALLINI Stefania CANTORE Saverio CAPODIFERRO and Felice Roberto GRASSI H Department of Dental Sciences and Surgery University of Bari Bari Italy. H Correspondence to Prof. . GRASSI Professor and Dean Department of Dental Sciences and Surgery - University of Bari G. Cesare n. 11-70124 BARI- ITALY. E-mail robertograssi@ Received Accepted Published Abstract We study the osteoinductive effect of the hyaluronic acid HA by using an esterified low-molecular HA preparation EHA as a coadjuvant in the grafting processes to produce bone-like tissue in the presence of employing autologous bone obtained from intra-oral sites to treat infra-bone defects without covering membrane. We report on 9 patients with periodontal defects treated by EHA and autologous grafting 4 males and 5 females all non smokers with a mean age of 43 8 years for females 40 0 years for males and 42 years for all the group in good health with a mean depth of mm of the infra-bone defects as revealed by intra-operative probes. Data were obtained at baseline before treatment and after 10 days and subsequently at 6 9 and 24 months after treatment. Clinical results showed a mean gain hi clinical attachment gCAL of of the treated sites confirmed by radiographic evaluation. Such results suggest that autologous bone combined with EHA seems to have good capabilities in accelerating new bone formation in the infra-bone defects. Key words Guided tissue regeneration bone graft Hyaluronic acid biomaterials. INTRODUCTION Hyaluronic acid HA is a natural occurring linear polysaccharide of the extracellular matrix of connective tissue synovial fluid and other tissues. HA structure consists of .