tailieunhanh - Báo cáo hóa học: " Circulating viral core and E1 antigen levels as supplemental markers for HCV Chronic hepatitis"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Circulating viral core and E1 antigen levels as supplemental markers for HCV Chronic hepatitis | BioMed Central Virology Journal Open Access Circulating viral core and E1 antigen levels as supplemental markers for HCV Chronic hepatitis Mostafa K El Awady 1 Yasmine S El Abd1 Hussein A Shoeb2 Ashraf A Tabll1 Alaa El Din MS Hosny2 Reem M El Shenawy1 Khaled Atef1 Noha G Bader El Din1 and Mahmoud M Bahgat3 Address Department of Biomedical Technology the National Research Center Dokki Egypt 2Department of Microbiology Faculty of Pharmacy Cairo University Cairo Egypt and 3Department of Medicinal Chemistry the National Research Center Dokki Giza Egypt Email Mostafa K El Awady - mkawady@ Yasmine S El Abd - yasminco@ Hussein A Shoeb - shoeb@ Ashraf A Tabll - ashraftabll@ Alaa El Din MS Hosny - mkawady@ Reem M El Shenawy - mkawady@ Khaled Atef - khaled_atef1@ Noha G Bader El Din - nohabadereldin@ Mahmoud M Bahgat - mkawady@ Corresponding author Published 01 September 2006 Received 28 September 2005 Accepted 01 September 2006 Virology journal 2006 3 67 doi l743-422X-3-67 This article is available from http content 3 1 67 2006 El Awady et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract_ The performance of polyclonal monospecific rabbit anti-sera raised against synthetic peptides derived from conserved HCV sequences of genotype 4 was evaluated for efficient detection of viral core and E1 antigens in circulating immune complexes ICs precipitated from 65 serum samples of HCV patients. The infection was established in those patients by the presence of HCV RNA in their sera. A novel enzyme-linked immunosorbent assay ELISA was developed