tailieunhanh - Báo cáo hóa học: " Isolation and characterization of a new simian rotavirus, YK-1"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Isolation and characterization of a new simian rotavirus, YK-1 | Virology Journal BioMed Central Open Access Isolation and characterization of a new simian rotavirus YK-I Larry E Westerman 1 2 Baoming Jiang1 2 Harold M McClure2 Lauren J Snipes-Magaldi1 Dixie D Griffin1 Gary Shin3 Jon R Gentsch1 and Roger I Glass1 2 Address 1Viral Gastroenteritis Team Respiratory and Enteric Viruses Branch Centers for Disease Control and Prevention Atlanta Georgia USA 2Yerkes National Primate Research Center Emory University Atlanta Georgia USA and 3Department of Ecology and Evolutionary Biology University of California at Los Angeles. Los Angeles California USA Email Larry E Westerman - larry@ Baoming Jiang - bjiang@ Harold M McClure - kays@ Lauren J Snipes-Magaldi - lmagaldi@ Dixie D Griffin - dixiegriffin@ Gary Shin - gtshin@ Jon R Gentsch - jgentsch@ Roger I Glass - rglass@ Corresponding author Published 31 May 2006 Received 30 June 2005 Virology Journal 2006 3 40 doi 1743-422X-3-40 Accepted 3 I May 2006 This article is available from http content 3 1 40 2006 Westerman et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract__ Background To effectively analyze the requirements for protection to rotavirus infection a reliable animal model that reasonably mimics infection and disease in humans is needed. A requirement for an effective animal model is the availability of appropriate rotavirus stocks for challenge. Results A new simian rotavirus designated YK- 1 was isolated from a 2-year-old immunodeficient pigtailed macaque with chronic diarrhea. YK-1 was distinguishable by electropherotype from the other simian .