tailieunhanh - Báo cáo hóa học: " Genetic diversity among five T4-like bacteriophages"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Genetic diversity among five T4-like bacteriophages | Virology Journal BioMed Central Open Access Genetic diversity among five T4-like bacteriophages James M Nolan 1 2 Vasiliy Petrov2 Claire Bertrand3 Henry M Krisch3 and Jim D Karam2 Address Department of Biological Sciences University of New Orleans 2000 Lakeshore Dr. New Orleans LA 70148 USA 2Department of Biochemistry Tulane University Health Sciences Center 1430 Tulane Ave. New Orleans LA 70112 USA and 3LMGM-CNRS UMR 5100 118 route de Narbonne 31062 Toulouse cedex 09 France Email James M Nolan - jnolan@ Vasiliy Petrov - vpetrov@ Claire Bertrand - Henry M Krisch - krisch@ Jim D Karam - karamoff@ Corresponding author Published 23 May 2006 Received 31 March 2006 Virology Journal 2006 3 30 doi I86 I743-422X-3-30 Accepted 23 May 2006 This article is available from http content 3 1 30 2006 Nolan et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract__ Background Bacteriophages are an important repository of genetic diversity. As one of the major constituents of terrestrial biomass they exert profound effects on the earth s ecology and microbial evolution by mediating horizontal gene transfer between bacteria and controlling their growth. Only limited genomic sequence data are currently available for phages but even this reveals an overwhelming diversity in their gene sequences and genomes. The contribution of the T4-like phages to this overall phage diversity is difficult to assess since only a few examples of complete genome sequence exist for these phages. Our analysis of five T4-like genomes represents half of the known T4-like genomes in GenBank. .