tailieunhanh - Báo cáo hóa học: " Chikungunya virus adapts to tiger mosquito via evolutionary convergence: a sign of things to come?"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Chikungunya virus adapts to tiger mosquito via evolutionary convergence: a sign of things to come? | Virology Journal BioMed Central Open Access Chikungunya virus adapts to tiger mosquito via evolutionary convergence a sign of things to come Xavier de Lamballerie 1 Eric Leroy2 Rémi N Charrel1 Konstantin Ttsetsarkin3 Stephen Higgs3 and Ernest A Gould1 Address 1Institut de Recherche pour le Développement UMR190 Unité des Virus Emergents Université de la Méditerranée Marseille France 2Institut de Recherche pour le Développement UMR190 CIRMF Franceville Gabon and 3Department of Pathology University of Texas Medical Branch Galveston Texas USA Email Xavier de Lamballerie - Eric Leroy - Rémi N Charrel - Konstantin Ttsetsarkin - kotsetsa@ Stephen Higgs - sthiggs@ Ernest A Gould - eag@ Corresponding author Published 27 February 2008 Received II January 2008 Accepted 27 February 2008 Virologyjournal 2008 5 33 doi 1743-422X-5-33 This article is available from http content 5 1 33 2008 de Lamballerie et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract_ Since 2004 several million indigenous cases of Chikungunya virus disease occurred in Africa the Indian Ocean India Asia and recently Europe. The virus usually transmitted by Aedes aegypti mosquitoes has now repeatedly been associated with a new vector Ae. Albopictus. Analysis of fulllength viral sequences reveals three independent events of virus exposure to Ae. Albopictus each followed by the acquisition of a single adaptive mutation providing selective advantage for transmission by this mosquito. This disconcerting and current unique example of evolutionary .