tailieunhanh - Báo cáo hóa học: " Avian influenza: genetic evolution under vaccination pressure"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Avian influenza: genetic evolution under vaccination pressure | Virology Journal BioMed Central Open Access Short report Avian influenza genetic evolution under vaccination pressure Magdalena Escorcia1 Lourdes Vazquez1 Sara T Mendez2 Andrea Rodriguez- Ropón3 Eduardo Lucio3 and Gerardo M Nava 1 4 Address 1Departamento de Producción Animal Aves. Facultad de Medicina Veterinaria y Zootecnia. Universidad Nacional Autónoma de Mexico D. F. 04510 Mexico 2Unidad de Genética de la Nutrición. Instituto Nacional de Pediatría D. F 04530 Mexico 3Investigación Aplicada S. A. de C. V. 7 Norte 416 Tehuacán Puebla 75700 Mexico and laboratory of Mucosal Biology. University of Illinois at Urbana-Champaign 61801 USA Email Magdalena Escorcia- magdaescorcia@ Lourdes Vazquez - lourdesvh_98@ Sara T Mendez - saratm@ Andrea Rodríguez-Ropón - ropon67@ Eduardo Lucio - elucio@ Gerardo M Nava - gerardomnava@ Corresponding author Published 24 January 2008 Virology Journal 2008 5 15 doi 1743-422X-5-15 Received 5 December 2007 Accepted 24 January 2008 This article is available from http content 5 1 15 2008 Escorcia et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Antigenic drift of avian influenza viruses AIVs has been observed in chickens after extended vaccination program similar to those observed with human influenza viruses. To evaluate the evolutionary properties of endemic AIV under high vaccination pressure around 2 billion doses used in the last 12 years we performed a pilot phylogenic analysis of the hemagglutinin HA gene of AIVs isolated from 1994 to 2006. This study demonstrates that Mexican low pathogenicity LP H5N2-AIVs are constantly undergoing genetic drifts. Recent AIV isolates 2002-2006 .