tailieunhanh - Báo cáo hóa học: " Role of HIV-1 subtype C envelope V3 to V5 regions in viral entry, coreceptor utilization and replication "

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Role of HIV-1 subtype C envelope V3 to V5 regions in viral entry, coreceptor utilization and replication | BioMed Central Virology Journal Research Open Access Role of HIV-I subtype C envelope V3 to V5 regions in viral entry coreceptor utilization and replication efficiency in primary T-lymphocytes and monocyte-derived macrophages Vasudha Sundaravaradant1 Suman RDast2 4 Rajesh Ramakrishnan1 5 Shobha Sehgal3 Sarla Gopalan3 Nafees Ahmad 1 and Shahid Jameel 2 Address Department of Immunobiology College of Medicine University of Arizona Tucson AZ 85724 USA 2Virology Group International Center for Genetic Engineering and Biotechnology New Delhi India 3Departments of Pathology and Obstetrics and Gynecology Post Graduate Institute of Medical Education and Research Chandigarh India 4NIAID National Institutes of Health Bethesda MD 20892 USA and 5Department of Molecular Virology Microbiology Baylor College of Medicine Houston TX 77030 USA Email Vasudha Sundaravaradan - vsvaradan@ Suman R Das - dassr@ Rajesh Ramakrishnan - ramakris@ Shobha Sehgal - sehgal@ Sarla Gopalan - Gopalan@ Nafees Ahmad - nafees@ Shahid Jameel - jameelshahid@ Corresponding authors tEqual contributors Published 24 November 2007 Virologyjournal 2007 4 126 doi l743-422X-4-126 Received 9 October 2007 Accepted 24 November 2007 This article is available from http content 4 1 126 2007 Sundaravaradan et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Several subtypes of HIV-1 circulate in infected people worldwide including subtype B in the United States and subtype C in Africa and India. To understand the biological properties of HIV-1 subtype C including cellular tropism virus entry replication efficiency and cytopathic effects we reciprocally .