tailieunhanh - Báo cáo hóa học: " Construction and characterization of recombinant flaviviruses bearing insertions between E and NS1 genes"

Tham khảo tài liệu 'báo cáo hóa học: " construction and characterization of recombinant flaviviruses bearing insertions between e and ns1 genes"', luận văn - báo cáo phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả | BioMed Central Virology Journal Methodology Open Access Construction and characterization of recombinant flaviviruses bearing insertions between E and NSI genes Myrna C Bonaldo 1 Samanta M Mello1 Gisela F Trindade1 Aymara A Rangel2 Adriana S Duarte1 Prisciliana J Oliveira1 Marcos S Freire2 Claire F Kubelka3 and Ricardo Galler2 Address 1Fundaẹão Oswaldo Cruz Instituto Oswaldo Cruz Laboratório de Biologia Molecular de Flavivirus Rio de Janeiro Fundaẹão Oswaldo Cruz. Avenida Brasil 4365 Manguinhos Rio de Janeiro RJ 21045-900 Brazil 2Fundaẹão Oswaldo Cruz Instituto de Tecnologia em Imunobiológicos Rio de Janeiro Brazil and 3Fundaẹão Oswaldo Cruz Instituto Oswaldo Cruz Laboratório de Imunologia Viral Rio de Janeiro Brazil Email Myrna C Bonaldo - mbonaldo@ Samanta M Mello - samello@ Gisela F Trindade - gfreitas@ Aymara A Rangel - aymara@ Adriana S Duarte - adriduar@ Prisciliana J Oliveira - priscilian@ Marcos S Freire - freire@ Claire F Kubelka - claire@ Ricardo Galler - rgaller@ Corresponding author Published 30 October 2007 Received 22 August 2007 Accepted 30 October 2007 Virology Journal 2007 4 115 doi 1743-422X-4-115 This article is available from http content 4 1 1 15 2007 Bonaldo et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The yellow fever virus a member of the genus Flavivirus is an arthropod-borne pathogen causing severe disease in humans. The attenuated yellow fever 17D virus strain has been used for human vaccination for 70 years and has several characteristics that are desirable for the development of new live attenuated vaccines. We described .