tailieunhanh - Báo cáo y học: "Mitral valve surgery for mitral regurgitation caused by Libman-Sacks endocarditis: a report of four cases and a systematic review of the literature"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Mitral valve surgery for mitral regurgitation caused by Libman-Sacks endocarditis: a report of four cases and a systematic review of the literature. | Bouma et al. Journal of Cardiothoracic Surgery 2010 5 13 http content 5 1 13 REVIEW JOTS JOURNAL OF CARDIOTHORACIC SURGERY Open Access Mitral valve surgery for mitral regurgitation caused by Libman-Sacks endocarditis a report of four cases and a systematic review of the literature 1 1 2 1 1 Wobbe Bouma Theo J Klinkenberg Iwan CC van der Horst Inez J Wijdh-den Hamer Michiel E Erasmus Ou B Al I I I Cl II IT m r4 c I I ỉ ulr . 2 i 1 I A K I ri 1 Marc Bijl Albert JH Suurmeijer Felix Zijlstra Massimo A Mariani Abstract Libman-Sacks endocarditis of the mitral valve was first described by Libman and Sacks in 1924. Currently the sterile verrucous vegetative lesions seen in Libman-Sacks endocarditis are regarded as a cardiac manifestation of both systemic lupus erythematosus SLE and the antiphospholipid syndrome APS . Although typically mild and asymptomatic complications of Libman-Sacks endocarditis may include superimposed bacterial endocarditis thromboembolic events and severe valvular regurgitation and or stenosis requiring surgery. In this study we report two cases of mitral valve repair and two cases of mitral valve replacement for mitral regurgitation MR caused by Libman-Sacks endocarditis. In addition we provide a systematic review of the English literature on mitral valve surgery for MR caused by Libman-Sacks endocarditis. This report shows that mitral valve repair is feasible and effective in young patients with relatively stable SLE and or APS and only localized mitral valve abnormalities caused by Libman-Sacks endocarditis. Both clinical and echocardiographic follow-up after repair show excellent mid- and long-term results. Introduction In 1924 Libman and Sacks first described four cases of non-bacterial verrucous vegetative endocarditis 1 . The sterile verrucous lesions of Libman-Sacks LS endocarditis Fig 1 show a clear predisposition for the mitral and aortic valves and are nowadays seen as both a cardiac manifestation of systemic