tailieunhanh - Báo cáo y học: " Analysis on the clinical features of 22 basaloid squamous cell carcinoma of the lung"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Analysis on the clinical features of 22 basaloid squamous cell carcinoma of the lung. | Wang et al. Journal of Cardiothoracic Surgery 2011 6 10 http content 6 1 10 JCTS JOURNAL OF CARDIOTHORACIC SURGERY RESEARCH ARTICLE Open Access Analysis on the clinical features of 22 basaloid squamous cell carcinoma of the lung Li C Wang13 Lei Wang13 Sabrina Kwauk2 Jennifer A Woo5 Li Q Wu 4 Hong Zhu4 Li Z Zhan3 Na L Sun 3 Lei Zhang1 3 Abstract Background Basaloid squamous cell carcinoma of the lung is a rare and highly malignant tumor mostly observed in the proximal bronchi. Basaloid squamous cell carcinoma of the lung cases typically show rapid clinical progression very poor prognosis and special pathological morphology. This project aimed to examine the clinical features of basaloid squamous cell carcinoma of the lung and the factors related to its prognosis and to compare survival outcomes between basaloid squamous cell carcinoma and poorly differentiated squamous cell carcinomas PDSC . Methods Between January 2004 and December 2008 pathological sections from basaloid squamous cell carcinoma and PDSC of the lung were collected and retrospectively analyzed at Tianjin Medical University Cancer Institute and Hospital. Data analysis was performed using Statistical Package for the Social Sciences . The Kaplan-Meier method was used to calculate the survival rate. Log-rank test was used to compare the differences in survival rate between the two groups. The factors influencing prognosis were analyzed using the Cox proportional hazard model. Results A total of 120 pathological sections were used in the analysis of this study-22 from basaloid squamous cell carcinoma cases and 98 from PDSC cases. Compared to the PDSC group the basaloid squamous cell carcinoma group had a larger proportion of female patients p however it had higher proportion of male smokers p . There were no statistically significant differences in survival rate between the two groups c2 p . Additionally prognosis of basaloid squamous cell .