tailieunhanh - Báo cáo y học: "The effect of tight glycaemic control, during and after cardiac surgery, on patient mortality and morbidity: A systematic review and meta-analysis"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: The effect of tight glycaemic control, during and after cardiac surgery, on patient mortality and morbidity: A systematic review and meta-analysis. | Haga et al. Journal of Cardiothoracic Surgery 2011 6 3 http content 6 1 3 JCTS JOURNAL OF CARDIOTHORACIC SURGERY RESEARCH ARTICLE Open Access The effect of tight glycaemic control during and after cardiac surgery on patient mortality and morbidity A systematic review and meta-analysis 1 11 1 1 1 Kristin K Haga Katie L McClymont Scott Clarke Rebecca S Grounds Ka Ying B Ng Daniel W Glyde Robert J Loveless 1 Gordon H Carter1 R Peter Alston2 Abstract Background Hyperglycaemia is a common occurrence during cardiac surgery however there remains some uncertainty surrounding the role of tight glycaemic control blood glucose 180 mg dL during and or after surgery. The aim of this study was to systematically review the literature to determine the effects of tight versus normal glycaemic control during and after cardiac surgery on measures of morbidity and mortality. Method The literature was systematically reviewed based on pre-determined search criteria for clinical trials evaluating the effect of tight versus normal glycaemic control during and or after cardiac surgery. Each paper was reviewed by two independent reviewers and data extracted for statistical analysis. Data from identified studies was combined using meta-analysis RevMan5 . The results are presented either as odds ratios OR or mean differences MD with 95 confidence intervals CIs . Results A total of seven randomised controlled trials RCTs were identified in the literature although not all trials could be used in each analysis. Tight glycaemic control reduced the incidence of early mortality death in ICU OR 95 CI of post-surgical atrial fibrillation odds ratio OR 95 CI the use of epicardial pacing OR 95 CI the duration of mechanical ventilation mean difference MD 95 CI and length of stay in the intensive care unit ICU MD 95 CI days. Measures of the time spent on mechanical ventilation I2 94 and time .

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