tailieunhanh - báo cáo hóa học:" Compressive loading at the end plate directly regulates flow and deformation of the basivertebral vein: an analytical study"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Compressive loading at the end plate directly regulates flow and deformation of the basivertebral vein: an analytical study | Journal of Orthopaedic Surgery and Research BioMed Central Research article Compressive loading at the end plate directly regulates flow and deformation of the basivertebral vein an analytical study Ming-Long Yeh1 2 Michael H Heggeness1 Hsiang-Ho Chen1 Jennifer Jassawalla1 and Zong-Ping Luo 1 Open Access Address Department of Orthopedic Surgery Baylor College of Medicine Houston TX USA and 2Biomedical Engineering Institute National Cheng-Kung University Tainan Taiwan ROC Email Ming-Long Yeh - mlyeh@ Michael H Heggeness - mhh@ Hsiang-Ho Chen - hsianghc@ Jennifer Jassawalla - jdjassaw@ Zong-Ping Luo - luo@ Corresponding author Published 27 December 2006 Received II April 2006 Journal of Orthopaedic Surgery and Research 2006 1 18 doi 1749-799X-1-18 Accepted 27 December 2006 This article is available from http content 1 1 18 2006 Yeh et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Metastatic diseases and infections frequently involve the spine. This is the result of seeding of the vertebral body by tumor cells or bacteria delivered by venous blood from Batson s plexus which is hypothesized to enter the vertebral body via the epidural veins. Isolated spinal segments deform significantly at the bony end plate when under compression. This deformation could cause a volume change of the vertebral body and may be accompanied by retrograde flow of venous blood. To date this process has not been investigated quantitatively. The purpose of this study was to determine the volume changes of the vertebral body and basivertebral vein for a vertebral body under compression. Methods A three-dimensional finite element mesh model of .