tailieunhanh - Báo cáo y học: " Five-year follow-up of angiographic disease progression after medicine, angioplasty, or surgery"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Five-year follow-up of angiographic disease progression after medicine, angioplasty, or surgery. | Borges et al. Journal of Cardiothoracic Surgery 2010 5 91 http content 5 1 91 JOTS JOURNAL OF CARDIOTHORACIC SURGERY RESEARCH ARTICLE Open Access Five-year follow-up of angiographic disease progression after medicine angioplasty or surgery Jorge Chiquie Borges Neuza Lopes Paulo R Soares Aécio FT Góis Noedir A Stolf Sergio A Oliveira Whady A Hueb Jose AF Ramires Abstract Background Progression of atherosclerosis in coronary artery disease is observed through consecutive angiograms. Prognosis of this progression in patients randomized to different treatments has not been established. This study compared progression of coronary artery disease in native coronary arteries in patients undergoing surgery angioplasty or medical treatment. Methods Patients 611 with stable multivessel coronary artery disease and preserved ventricular function were randomly assigned to CABG PCI or medical treatment alone MT . After 5-year follow-up 392 patients 64 underwent new angiography. Progression was considered a new stenosis of 50 in an arterial segment previously considered normal or an increased grade of previous stenosis 20 in nontreated vessels. Results Of the 392 patients 136 underwent CABG 146 PCI and 110 MT. Baseline characteristics were similar among treatment groups except for more smokers and statin users in the MT group more hypertensives and lower LDL-cholesterol levels in the CABG group and more angina in the PCI group at study entry. Analysis showed greater progression in at least one native vessel in PCI patients 84 compared with CABG 57 and MT 74 patients p . LAD coronary territory had higher progression compared with LCX and RCA P . PCI treatment hypertension male sex and previous MI were independent risk factors for progression. No statistical difference existed between coronary events and the development of progression. Conclusion The angioplasty treatment conferred greater progression in native coronary arteries especially .

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