tailieunhanh - Báo cáo y học: "Early and mid term mortality after coronary artery bypass grafting in women depends on the surgical protocol: retrospective analysis of 3441 on- and off-pump coronary artery bypass grafting procedures"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Early and mid term mortality after coronary artery bypass grafting in women depends on the surgical protocol: retrospective analysis of 3441 on- and off-pump coronary artery bypass grafting procedures. | Eifert et al. Journal of Cardiothoracic Surgery 2010 5 90 http content 5 1 90 JOTS JOURNAL OF CARDIOTHORACIC SURGERY RESEARCH ARTICLE Open Access Early and mid term mortality after coronary artery bypass grafting in women depends on the surgical protocol retrospective analysis of 3441 on- and off-pump coronary artery bypass grafting procedures Sandra Eifert Eckehard Kilian Andres Beiras-Fernandez Gerd Juchem Bruno Reichart Peter Lamm Abstract Background Since 2002 MI and stroke not cancer are leading causes of death in women. We studied 30-days and 1 year mortality of 3441 patients undergoing coronary artery bypass grafting CABG operations in our institution performed either conventionally or off pump OPCAB . Our objective was to investigate the gender-related mortality in both groups. Patients and Methods Between 2004 and 2008 3441 patients 733 women 2708 men underwent CABG. 252 women and 854 men were operated using OPCAB 481 women and 1854 men using extracorporeal circulation ECC . Medical data was prospectively entered and retrospectively reviewed. 30-days and one year mortality rates were analyzed with Kaplan-Meier estimates and Cox proportional hazards models. Linear and logistic regression models were used to test gender differences. Results a 30-day mortality using ECC in women vs. in men p . One year ECC mortality in women vs. in men p . b OPCAB 30-days and 1 year mortality in women measured . Mortality in men was after 30 days and after one year c gender specific mortality 30 days mortality in women was using OPCAB and using ECC p one year mortality in women was using OPCAB vs. using ECC p . In men 30-days mortality in OPCAB was one year mortality was using ECC early and late mortality was and . Conclusions Female gender is a strong independent predictor and risk factor of increased early and midterm postoperative mortality rates when ECC is