tailieunhanh - Báo cáo y học: "Primary leiomyosarcoma of the right atrium: a case report and literature updat"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Primary leiomyosarcoma of the right atrium: a case report and literature update. | Parissis et al. Journal of Cardiothoracic Surgery 2010 5 80 http content 5 1 80 JOTS JOURNAL OF CARDIOTHORACIC SURGERY CASE REPORT Open Access Primary leiomyosarcoma of the right atrium a case report and literature update Haralabos Parissis 1 Mohamad Taukeer Akbar2 Vincent Young3 Abstract Leiomyosarcoma of the right atrium is a very rare cardiac tumor. Various combinations of treatments including resection or transplant surgery and Chemotherapy have been advocated. We report a case of a man who presented with pulmonary embolism secondary to right atrial leiomyosarcoma. He was managed by excision of the tumor and reconstruction of the right atrium with autologous pericardium. Postoperatively tumor dissemination was controlled with adjuvant chemotherapy. A vigorous attempt aiming at tumor clearance followed by adjuvant multimodality therapy along with a tumor surveillance program may improve survival. Introduction Primary cardiac malignancies PCM are rare. The prevalence of primary cardiac malignancies has been estimated at only - 1 . Primary cardiac tumors are detected in 1 in a 1000 autopsies and PCM are found in only about of autopsies 2 3 . Metastatic cardiac tumors are a 100-fold more common than primary lesions. The majority of Primary Cardiac tumors are benign with half of them being myxomas 4 and approximately 25 of primary cardiac neoplasms are malignant. Among malignant primary cardiac tumors the most reported are those histopathologically considered as undifferentiated followed by angiosarcomas with leiomyosarcomas being rare. Due to delayed presentation there is infrequently a systemic spread at the time of diagnosis. As a result management of this condition is difficult and controversial. Case Report We present a case of a 36 year old male who was admitted with recent onset of shortness of breath. CT pulmonary angiogram demonstrated large right sided pulmonary emboli Figure 1 . Moreover a filling defect was