tailieunhanh - Báo cáo y học: "Hyperbaric oxygen therapy as an adjunctive treatment for sternal infection and osteomyelitis after sternotomy and cardiothoracic surgery"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Hyperbaric oxygen therapy as an adjunctive treatment for sternal infection and osteomyelitis after sternotomy and cardiothoracic surgery. | Yu et al. Journal of Cardiothoracic Surgery 2011 6 141 http content 6 1 141 JCTS JOURNAL OF CARDIOTHORACIC SURGERY RESEARCH ARTICLE Open Access Hyperbaric oxygen therapy as an adjunctive treatment for sternal infection and osteomyelitis after sternotomy and cardiothoracic surgery Wen-Kuang Yu1 Yen-Wen Chen1 2 Huei-Guan Shie1 Te-Cheng Lien1 2 Hsin-Kuo Kao1 2 and Jia-Horng Wang1 Abstract Purpose A retrospective study to evaluate the effect of hyperbaric oxygen HBO2 therapy on sternal infection and osteomyelitis following median sternotomy. Materials and methods A retrospective analysis of patients who received sternotomy and cardiothoracic surgery which developed sternal infection and osteomyelitis between 2002 and 2009. Twelve patients who received debridement and antibiotic treatment were selected and six of them received additional HBO2 therapy. Demographic clinical characteristics and outcome were compared between patients with and without HBO2 therapy. Results HBO2 therapy did not cause any treatment-related complication in patients receiving this additional treatment. Comparisons of the data between two study groups revealed that the length of stay in ICU days vs. days p duration of invasive 4 days vs. days p and non-invasive 4 days vs. days p positive pressure ventilation were all significantly lower in patients with additional HBO2 therapy as compared to patients without HBO2 therapy. Hospital mortality was also significantly lower in patients who received HBO2 therapy 0 case vs. 3 cases p as compared to patients without the HBO2 therapy. Conclusions In addition to primary treatment with debridement and antibiotic use HBO2 therapy may be used as an adjunctive and safe treatment to improve clinical outcomes in patients with sternal infection and osteomyelitis after sternotomy and cardiothoracic surgery. Keywords hyperbaric oxygen sternal infection osteomyelitis .