tailieunhanh - Báo cáo y học: "Circadian phase response curves to light in older and young women and me"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Circadian phase response curves to light in older and young women and me. | Journal of Circadian Rhythms BioMed Central Open Access Circadian phase response curves to light in older and young women and men Daniel F Kripke 1 Jeffrey A Elliott1 Shawn D Youngstedt2 and Katharine M Rex1 Address Department of Psychiatry and Sam and Rose Stein Institute on Aging University of California San Diego 0667 La Jolla California 92093-0667 USA and 2Department of Exercise Science Norman J. Arnold School of Public Health University of South Carolina Columbia SC 29208 USA and Dorn VA Medical Center Columbia SC 29209 USA Email Daniel F Kripke - DKripke@ JeffreyAElliott-JElliott@ Shawn D Youngstedt - Syoungst@ Katharine M Rex - KRex@ Corresponding author Published 10 July 2007 Received 8 May 2007 Journal of Circadian Rhythms 2007 5 4 doi 1740-3391-5-4 Accepted I0 July 2007 This article is available from http content 5 1 4 2007 Kripke et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract__ Background The phase of a circadian rhythm reflects where the peak and the trough occur for example the peak and trough of performance within the 24 h. Light exposure can shift this phase. More extensive knowledge of the human circadian phase response to light is needed to guide light treatment for shiftworkers air travelers and people with circadian rhythm phase disorders. This study tested the hypotheses that older adults have absent or weaker phase-shift responses to light 3000 lux and that women s responses might differ from those of men. Methods After preliminary health screening and home actigraphic recording baselines 50 young adults ages 18-31 years and 56 older