tailieunhanh - Báo cáo y học: "The relationship between the rate of melatonin excretion and sleep consolidation for locomotive engineers in natural sleep setting"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: The relationship between the rate of melatonin excretion and sleep consolidation for locomotive engineers in natural sleep settings. | Journal of Circadian Rhythms BioMed Central Short paper The relationship between the rate of melatonin excretion and sleep consolidation for locomotive engineers in natural sleep settings Gregory D Roach 1 Kathryn J Reid2 Sally Ferguson1 and Drew Dawson1 Open Access Address Centre for Sleep Research University of South Australia City East Campus Adelaide SA 5000 Australia and 2Department of Neurology Northwestern University Chicago IL 60208 USA Email Gregory D Roach - Kathryn J Reid - k-reid@ Sally Ferguson - Drew Dawson - Corresponding author Published 18 August 2006 Received 03 May 2006 Journal of Circadian Rhythms 2006 4 8 doi l740-339l-4-8 Accepted 18 August 2006 This article is available from http content 4 l 8 2006 Roach et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The aim of the study was to examine the role that melatonin production plays in the regulation of sleep consolidation in a population of shiftworkers working and sleeping in their natural environments. Methods 253 locomotive engineers 249 male 4 female mean age years participated in the study for a 2-week period whilst working their normal roster patterns. Participants recorded details for all sleep periods in a sleep diary and collected urine samples during each day s main sleep period. The samples were subsequently assayed for the metabolite of melatonin in urine 6-sulphatoxymelatonin aMT6s and the rate of excretion during main sleep periods was calculated. Results Separate one-way factorial ANOVAs revealed a significant effect of time of sleep onset on aMT6s excretion rate sleep duration and .

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