tailieunhanh - Báo cáo y học: " Recurrent pericardial effusion after cardiac surgery: the use of colchicine after recalcitrant conventional therapy"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Recurrent pericardial effusion after cardiac surgery: the use of colchicine after recalcitrant conventional therapy. | Dainese et al. Journal of Cardiothoracic Surgery 2011 6 96 http content 6 1 96 JCTS JOURNAL OF CARDIOTHORACIC SURGERY CASE REPORT Open Access Recurrent pericardial effusion after cardiac surgery the use of colchicine after recalcitrant conventional therapy Luca Dainese Antioco Cappai and Paolo Biglioli Abstract Pericardial effusion represents a common postoperative complication in cardiac surgery. Nonetheless it can be resistant to conventional therapy leading to prolonged in-hospital stay and worsening of clinical conditions. Recent literature shows that colchicine therapy should be useful in the treatment of recurrent post surgical pericardial effusion. Hereby we report the case of a patient with postsurgical recurrent effusion treated with colchicine and a review of literature concerning the use of this old drug. Text Pericardial effusion represents a common postoperative complication in cardiac surgery. Sometimes it can be resistant to conventional therapy leading to prolonged in-hospital stay and worsening of clinical condition. In the last twenty years colchicine was reported to be clinical effective although most of Authors have published their experience based upon incomplete and sometimes anedoctical experience. Starting from a case of patients successfully treated with this drug we present a review concerning the more recent and statistically based studies about the treatment with this old but actually drug. Case Report A 47-year-old male underwent elective coronary artery bypass grafting. The postoperative intensive care unit stay was uneventful the postoperative echocardiogram did not showed abnormalities and the patient was discharged on 100 mg cardioaspirin once daily. Five days after the discharge the patient developed ongoing dyspnea and was referred to our department. The echocardiogram demonstrated a large amount of pericardial effusion. Subxiphoid pericardiotomy was performed. The analysis of pericardial fluid .