tailieunhanh - Báo cáo hóa học: "Dermal absorption of aromatic amines in workers with different skin lesions: a report on 4 cases"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Dermal absorption of aromatic amines in workers with different skin lesions: a report on 4 cases | Journal of Occupational Medicine and Toxicology BioMed Central Case report Open Access Dermal absorption of aromatic amines in workers with different skin lesions a report on 4 cases Gintautas Korinth 1 Tobias Weiss2 Jurgen Angerer1 and Hans Drexler1 Address institute and Out-Patient Clinic of Occupational Social and Environmental Medicine University of Erlangen-Nuremberg Schillerstrasse 25 29 D-91054 Erlangen Germany and 2Research Institute for Occupational Medicine of the Ruhr University of Bochum BGFA Burkle-de-la-Camp Platz 1 D-44789 Bochum Germany Email Gintautas Korinth - Tobias Weiss - Jurgen Angerer - Hans Drexler - Corresponding author Published 19 July 2006 Received 20 March 2006 Journal of Occupational Medicine and Toxicology 2006 1 17 doi 1745-6673-1-17 Accepted 19 July 2006 This article is available from http content 1 1 17 2006 Korinth et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract There are only few studies about the relationship of skin lesions and the percutaneous uptake of hazardous substances in exposed workers. Several aromatic amines are well known carcinogens for humans and or animals. This case report emphasizes the relevance of dermal absorption of the aromatic amine ortho-toluidine considering four workers with different skin status healthy erythematous and burned skin as well as dishydrotic eczema during the vulcanisation process of rubber products in a components supplier plant for automobile industry. The results of our case report show that dermal absorption of o-toluidine through damaged epidermal .