tailieunhanh - báo cáo hóa học: " Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte "

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte | Journal of Neuroinflammation BioMed Central Research Open Access Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer s disease mice Michelle C Janelsins 2 3 Michael A Mastrangelo3 Salvatore Oddo4 Frank M LaFerla4 Howard J Federoff1 2 3 and William J Bowers 1 3 Address Department of Neurology University of Rochester School of Medicine and Dentistry Rochester New York 14642 USA 2Department of Microbiology and Immunology University of Rochester School of Medicine and Dentistry Rochester New York 14642 USA 3Center for Aging and Developmental Biology University of Rochester School of Medicine and Dentistry Rochester New York 14642 USA and 4Department of Neurobiology and Behavior University of California Irvine California 92697 USA Email Michelle C Janelsins - michelle_janelsins@ Michael AMastrangelo - michael_mastrangelo@ Salvatore Oddo - soddo@ Frank M LaFerla - laferla@ Howard J Federoff - howard_federoff@ William J Bowers - william_bowers@ Corresponding author Published 18 October 2005 Received 15 September 2005 Journal ofNeuroinflammation 2005 2 23 doi l742-2094-2-23 Accepted 18 October 2005 This article is available from http content 2 1 23 2005 Janelsins et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Alzheimer s disease is a complex neurodegenerative disorder characterized pathologically by a temporal and spatial progression of beta-amyloid AB deposition neurofibrillary tangle formation and synaptic degeneration. .

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