tailieunhanh - Báo cáo y học: "Characteristics of HIV-infected women and factors associated with HCV seropositivity in the Republic of Georgia"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Characteristics of HIV-infected women and factors associated with HCV seropositivity in the Republic of Georgia. | Chkhartishvili et al. AIDS Research and Therapy 2011 8 25 http content 8 1 25 AIDS RESEARCH AND THERAPY RESEARCH Open Access Characteristics of HIV-infected women and factors associated with HCV seropositivity in the Republic of Georgia Nikoloz Chkhartishvili1 Louise-Anne McNutt2 Perry F Smith3 and Tengiz Tsertsvadze1 4 Abstract Background The aim of this study was to describe the extent of the HIV epidemic among women in the Republic of Georgia and to identify factors associated with HCV co-infection in this population. Findings All women aged 18 years who were diagnosed with HIV between 1989 and 2006 were identified through the National HIV AIDS surveillance database. Medical records were reviewed for demographic characteristics risk factors and HCV serostatus. A total of 249 women were identified. Only 4 declared injection drug use IDU sex work was reported by 9 . Substantial risk factors were identified among the women s sexual partners nearly 69 of whom were IDUs 84 were HIV positive and 66 HCV positive. Seventeen percent of women were seropositive for HCV. Factors significantly associated with HCV seropositivity in bivariate analyses among non-IDU women were partner IDU Prevalence ratio PR 95 CI and partner HCV PR 95 CI . Conclusions The HIV epidemic in the Republic of Georgia is closely tied to the IDU community. Evidence-based interventions targeting IDU and partners of IDU are urgently required to halt the spread of the HIV epidemic in the country. Findings The Newly Independent States NIS of Eurasia have the highest rates of HIV infection in the region 1 2 . The HIV epidemic here has been closely linked with the socioeconomic and political upheavals of the early 1990s and the collapse of the Soviet Union. The emergence of drug markets and injection drug use IDU is now the major driver of the epidemic in the region 3 4 . The burgeoning IDU population was accompanied by an explosive spread of hepatitis C .