tailieunhanh - Báo cáo y học: "Experiences in conducting multiple community-based HIV prevention trials among"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Experiences in conducting multiple community-based HIV prevention trials among . | Ramjee et al. AIDS Research and Therapy 2010 7 10 http content 7 1 10 AIDS RESEARCH AND THERAPY RESEARCH Open Access Experiences in conducting multiple community-based HIV prevention trials among women in KwaZulu-Natal South Africa Gita Ramjee Nicola Coumi Nozizwe Dladla-Qwabe Shay Ganesh Sharika Gappoo Roshini Govinden Vijayanand Guddera Rashika Maharaj Jothi Moodley Neetha Morar Sarita Naidoo and Thesla Palanee Abstract Background South Africa with its scientific capacity good infrastructure and high HIV incidence rates is ideally positioned to conduct large-scale HIV prevention trials. The HIV Prevention Research Unit of the South African Medical Research Council conducted four phase III and one phase IIb trials of women-initiated HIV prevention options in KwaZulu-Natal between 2003 and 2009. A total of 7046 women participated with HIV prevalence between 25 and 45 and HIV incidence ranging from per year. Unfortunately none of the interventions tested had any impact on reducing the risk of HIV acquisition however extremely valuable experience was gained lessons learned and capacity built while the communities gained associated benefits. Experience Our experience in conducting these trials ranged from setting up community partnerships to developing clinical research sites and dissemination of trial results. Community engagement included setting up communitybased research sites with approval from both political and traditional leaders and developing community advisory groups to assist with the research process. Community-wide education on HIV sexually transmitted infection prevention treatment and care was provided to over 90 000 individuals. Myths and misconceptions were addressed through methods such as anonymous suggestion boxes in clinic waiting areas and intensive education and counselling. Attempts were made to involve male partners to foster support and facilitate recruitment of women. Peer educator programmes were initiated to