tailieunhanh - Báo cáo y học: " Estimating the impact of expanded access to antiretroviral therapy on maternal, paternal and double orphans in sub-Saharan Africa, 2009-2020"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Estimating the impact of expanded access to antiretroviral therapy on maternal, paternal and double orphans in sub-Saharan Africa, 2009-2020. | Anema et al. AIDS Research and Therapy 2011 8 13 http content 8 1 13 AIDS RESEARCH AND THERAPY RESEARCH Open Access Estimating the impact of expanded access to antiretroviral therapy on maternal paternal and double orphans in sub-Saharan Africa 2009-2020 1 3 3 34 Aranka Anema 1 Christopher G Au-Yeung Michel Joffres Angela Kaida Krisztina Vasarhelyi Steve Kanters 1 Julio SG Montaner1 2 Robert S Hogg1 3 Abstract Background HIV AIDS has orphaned million children in sub-Saharan Africa. Expanded antiretroviral therapy ART use may reduce AIDS orphanhood by decreasing adult mortality and population-level HIV transmission. Methods We modeled two scenarios to measure the impact of adult ART use on the incidence of orphanhood in 10 sub-Saharan African countries from 2009 to 2020. Demographic model data inputs were obtained from cohort studies UNAIDS UN Population Division WHO and the US Census Bureau. Results Compared to current rates of ART uptake universal ART access averted million more AIDS orphans by year 2020 including million maternal million paternal and million double orphans. The number of AIDS orphans averted was highest in South Africa thousand and Nigeria thousand and lowest in Zimbabwe thousand and Côte d Ivoire thousand . Conclusion Universal ART use may significantly reduce orphanhood in sub-Saharan Africa. Introduction An estimated million children aged 0 to 17 years in sub-Saharan Africa have lost one or both parents due to human immunodeficiency virus acquired immune deficiency syndrome HIV AIDS since the beginning of the epidemic 1 . Studies suggest that orphans in subSaharan Africa may have poor quality of life and health including reduced access to basic material goods and retention in education 2 and elevated psychological distress and symptoms of depression 3 4 . Orphans may be at heightened risk of acquiring HIV due to engagement in early and unprotected sex and .