tailieunhanh - Báo cáo y học: " Novel multi-component nanopharmaceuticals derived from poly(ethylene) glycol, retro-inverso-Tat nonapeptide and saquinavir demonstrate combined anti-HIV effect"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Novel multi-component nanopharmaceuticals derived from poly(ethylene) glycol, retro-inverso-Tat nonapeptide and saquinavir demonstrate combined anti-HIV effects. | AIDS Research and Therapy BioMed Central Research Open Access Novel multi-component nanopharmaceuticals derived from poly ethylene glycol retro-inverso-Tat nonapeptide and saquinavir demonstrate combined anti-HIV effects Li Wan1 Xiaoping Zhang1 Simi Gunaseelan1 Shahriar Pooyan1 Olivia Debrah1 Michael J Leibowitz2 3 Arnold B Rabson2 3 Stanley Stein1 3 and Patrick J Sinko 1 3 Address Department of Pharmaceutics Ernest Mario School of Pharmacy Rutgers University 160Frelinghuysen Road Piscataway New Jersey 08854-0789 USA 2Department of Molecular Genetics Microbiology and Immunology Robert Wood Johnson Medical School University of Medicine and Dentistry of New Jersey Piscataway New Jersey 08854 USA and 3Cancer Institute of New Jersey New Brunswick New Jersey 089032681 USA Email Li Wan - liwan@ Xiaoping Zhang - xzhang@ Simi Gunaseelan - simig@ Shahriar Pooyan - spooyan4@ Olivia Debrah - livina@ Michael J Leibowitz - leibowit@ Arnold B Rabson - rabson@ Stanley Stein - ststein@ Patrick J Sinko - sinko@ Corresponding author Published 24 April 2006 Received 15 July 2005 AIDS Research and Therapy 2006 3 12 doi 1742-6405-3-12 Accepted 24 April 2006 This article is available from http content 3 1 12 2006 Wan et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Current anti-AIDS therapeutic agents and treatment regimens can provide a dramatically improved quality of life for HIV-positive people many of whom have no detectable viral load for prolonged periods of time. Despite this curing AIDS remains an elusive goal partially due to the occurrence of drug .