tailieunhanh - Báo cáo y học: "Scutellaria baicalensis decreases ritonavir-induced nausea."

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Scutellaria baicalensis decreases ritonavir-induced nausea. | AIDS Research and Therapy BioMed Central Research Scutellaria baicalensis decreases ritonavir-induced nausea Open Access Han Aung1 2 Sangeeta Mehendale1 2 Wei-Tien Chang1 2 Chong-Zhi Wang1 2 Jing-Tian Xie1 2 and Chun-Su Yuan 1 2 3 Address Tang Center for Herbal Medicine Research Pritzker School of Medicine. The University of Chicago IL 60637 USA 2Departments of Anesthesia Critical Care. Pritzker School of Medicine. The University of Chicago IL 60637 USA and 3Committee on Clinical Pharmacology and Pharmacogenomics. Pritzker School of Medicine. The University of Chicago IL 60637 USA Email Han Aung - haung@ Sangeeta Mehendale - smehendale@ Wei- Tien Chang - wchang@ Chong-Zhi Wang - czwang@ Jing-Tian Xie - jtxie@ Chun-Su Yuan - cyuan@ Corresponding author Published 20 December 2005 Received 15 August 2005 . ArD_ AAAC J . A I IO I7A AAnc 1 n Accepted 20 December 2005 AIDS Research and Therapy 2005 2 12 doi 1742-6405-2-12 This article is available from http content 2 1 12 2005 Aung et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Protease inhibitors particularly ritonavir causes significant gastrointestinal disturbances such as nausea even at low doses. This ritonavir-induced nausea could be related to its oxidative stress in the gut. Alleviation of drug-induced nausea is important in effectively increasing patients compliance and improving their quality of life. Conventional anti-emetic drugs can only partially abate the symptoms in these patients and their cost has also been a concern. Rats respond to nausea-producing emetic stimuli by increasing .