tailieunhanh - Biosensors Emerging Materials and Applications Part 14

Tham khảo tài liệu 'biosensors emerging materials and applications part 14', kỹ thuật - công nghệ, cơ khí - chế tạo máy phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả | 512 Biosensors - Emerging Materials and Applications biosensors in this system Carrara et al. 2009 de Vasconcelos et al. 2009 Saravan et al. 2008 . In this study the covalent bonding on an optimized GID is connected antibodies via epoxy-silanisation Saravan et al. 2008 this method is less prone to sensitivity the other less cheap silicon dioxide with a high-sensitive measurement applied to nanocrystalline diamonds Quershi et al. 2009 . GID arrays of silicon oxide surface with a thick layer of tungsten first a thin gold layer is coated in advance to allow for the creation of an easier way. According to this structure the capacitor arrays includes 24 fingers GID Quershi et al. 2010 . First arrays were treated with MPA to SAM created layer free carboxyl groups was activated by NHS EDC and antibody is ready for immobilization. Phase of antibody immobilization was created in two formats the first method each GID capacitor with a pure antibody while the second method equal amounts of multiple antibodies CRP TNF and IL-6 was co-immobilized. Dielectric parameters of different antigens were treated arrays were prepared. BSA was used as a non-specific protein for a negative control. Limits for the determination of biomarkers measured in linear 25pg mL to 25ng mL. The complex dielectric constant is a result of the change in dipole momenttes of biomolecules which differences amino acid sequence of elements that can bring about change in the dipole momentte Antosiewicz 1995 . To the determination of several biomarkers of cancer as it is known to determine the accuracy of diagnosis of cancer is increasing. Most of the other proteins secreted as a result of the cancer biomarker can be found in a unified manner. Quareshi et al. developed for multiple analyses by allowing the disease to other singleanalyte immunosensors advantageous and gives accurate results in this array technology. In addition the silicon oxide background is fast simple and sensitive measurements allowing the .