tailieunhanh - Biosensors Emerging Materials and Applications Part 12

Tham khảo tài liệu 'biosensors emerging materials and applications part 12', kỹ thuật - công nghệ, cơ khí - chế tạo máy phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả | 432 Biosensors - Emerging Materials and Applications days without any considerable loss of activity when stored at 4 C between the measurements Narang et al. 2010 . Conducting polymer-based electrochemical sensors have shown numerous advantages in a number of areas related to human health such as the diagnosis of infectious diseases genetic mutations drug discovery forensics and food technology due to their simplicity and high sensitivity. One of the most promising group of conductive polymers is poly 3 4-ethylenedioxythiophene PEDOT or PEDT and its derivatives due to their attractive properties high stability high conductivity up to 400-600 S cm and high transparency Rozlosnik et al. 2009 Nikolou et al. 2008 . Organic transistors based on PEDT doped with poly styrene sulfonic acid PEDT PSS offer enormous potential for facile processing of small portable and inexpensive sensors ideally suited for point-of-care analysis. They can be used to detect a wide range of analytes for a variety of possible applications in fields such as health care medical diagnostics environmental monitoring airborne chemicals water contamination etc. and food industry smart packaging . These transistors are considered to be excellent candidates for transducers for biosensors because they have the ability to translate chemical and biological signals into electronic signals with high sensitivity. Furthermore fuctionalization of PEDT PSS films with a chemical or biological receptors can lead to high specificity Nikolou et al. 2008 . Bioanalytical application of Glycerol oxidase GO as bioselective element of amperometric biosensors The enzymatic glycerol transformation using oxidases results in generating of electrochemically active hydrogen peroxide. An amperometric GO-based biosensor is considered to be an attractive alternative over other biosensors. To construct glycerol selective biosensors a GO preparation with a specific activity of pmole-miiT -mg-1 of protein were used for .