tailieunhanh - CURRENT CLINICAL NEUROLOGY - PART 5

Tâm thần rối loạn chức năng có thể được chỉ mang thiệt hại cho nhiều vùng não, mặc dù các khu vực liên quan đến phổ biến nhất bao gồm dải vận động của vỏ não, chất trắng dưới vỏ não, hạch nền và tiểu não. Bởi vì nguồn cung cấp microvasculature hạch nền, tiểu não | 134 Jefferson et al. . Psychomotor Functions Psychomotor functioning is a complex cognitive domain that can be loosely defined as a speeded motor response that may or may not involve some cognitive load . Trail Making Test Part A or Finger Tapping Test respectively . Although this is somewhat of an arbitrary dichotomization neuropsychological assessment of psychomotor functioning often involves tests of manual dexterity . motor-based and or information processing speed and visuomotor tracking . cognitivebased . Psychomotor dysfunction can be indicative of damage to numerous brain regions although the most commonly implicated regions include the motor strip of the cortex subcortical white matter basal ganglia and cerebellum. Because the microvasculature supply source for the basal ganglia cerebellum and subcortical white matter becomes vulnerable with age it is plausible that psychomotor functioning may be implicated in conditions involving microvascular disease. Studies of psychomotor dysfunction on neuropsychological testing among VaD samples are lacking particularly research examining performance on motor-based psychomotor tasks of manual dexterity and speeded motor functions. There is little doubt that VaD may result in significant disruption of subcortical motor systems as evidenced by reports of vascular Parkinsonism 22 . However few studies have empirically examined the impact of motor skills on psychomotor function in VaD. That which does exist has focused on between-group differences with AD samples with mixed results. For instance Almkvist et al. 23 reported a significant difference between AD and VaD patients on a measure of fine motor speed whereas Lamar and others 24 found no such between-group difference. Comparison data between normal controls and VaD patients on neuropsychological tasks assessing manual dexterity and fine motor speed are rare. In contrast the preponderance of literature related to this topic has emphasized those .