tailieunhanh - Parkinson disease and related disorders part - part 5

Uẩn từ đột biến và tự nhiên loại protein alpha-synuclein và NAC peptide gây chết tế bào apoptosis trong tế bào u nguyên bào thần kinh của con người bằng cách hình thành của bản beta và như sợi amyloid | 238 Y. MIZUNO ET AL. Chen R Gosavi NS Langston JW et al. 2003 . Parkin mutations are rare in patients with young-onset parkinsonism in a US population. Parkinsonism Relat Disord 9 309-312. Chen X Silva HAR Pettenati MJ et al. 1995 . The human NACP a-synucleiin gene chromosome assignment to and TaqI RFLP analysis. Genomics 26 425 427. Chiba-Falek O Nussbaum RL 2001 . Effect of allelic variation at the NACP-Rep1 repeat upstream of the alpha-synu-clein gene SNCA on transcription in a cell culture luciferase reporter system. Hum Mol Genet 10 3101-3109. Choi P Snyder H Petrucelli L et al. 2003 . SEPT5_v2 is a parkin-binding protein. Brain Res Mol Brain Res 117 179-189. Choi W Zibaee S Jakes R et al. 2004 . Mutation E46K increases phospholipid binding and assembly into filaments of human alpha-synuclein. FEBS Lett 576 363-368. Chung KKK Zhang Y Lim KL et al. 2001 . Parkin ubiquitinates the a-synuclein-interacting protein synphilin-1 implications for Lewy-body formation in Parkinson disease. Nat Med 7 1144-1150. Church SL Grant JW Meese EU et al. 1992 . Sublocalization of the gene encoding manganese superoxide dismutase MnSOD sod2 to 6q25 by fluorescence in situ hybridization and somatic cell hybrid mapping. Genomics 14 823-825. Clarimon J Johnson J Dogu O et al. 2005 . Defining the ends of parkin exon 4 deletions in two different families with Parkinson s disease. Am J Med Genet B Neuropsy-chiatr Genet 133 120-123. Clark LN Afridi S Mejia-Santana H et al. 2004 . Analysis of an early-onset Parkinson s disease cohort for DJ-1 mutations. Mov Disord 19 796-800. Corti O Hampe C Koutnikova H et al. 2003 . The p38 subunit of the aminoacyl-tRNA synthetase complex is a parkin substrate linking protein biosynthesis and neurodegeneration. Hum Mol Genet 12 1427-1437. Cuervo AM Stefanis L Fredenburg R et al. 2004 . Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy. Science 305 1292-1295. Dekker M Bonifati V van Swieten J et al. 2003 . Clinical