tailieunhanh - Báo cáo khoa học: " Multilobular tumour of the caudal cranium causing severe cerebral and cerebellar compression in a dog"

Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: Multilobular tumour of the caudal cranium causing severe cerebral and cerebellar compression in a dog | J. Vet. Sci. 2009 10 1 81-83 DOI Short Communication JOURNAL OF Veterinary Science Multilobular tumour of the caudal cranium causing severe cerebral and cerebellar compression in a dog 1 1 2 1 1 Vassilios Psychas Panayiotis Loukopoulos Zoe S. Polizopoulou Georgios Sofianidis Pathology Laboratory 2Diagnostic Laboratory Faculty of Veterinary Medicine Aristotle University 54124 Thessaloniki Greece Multilobular tumour of bone MTB is an uncommon tumour and is usually located in the skull. A 13-year-old mixed breed dog was presented with a two-week history of progressively worsening vestibular dysfunction and cognitive abnormalities it appeared demented and showed asymmetric ataxia and hypermetria of all limbs. The owner opted to have the animal euthanised. Necropsy revealed a large mass occupying the right occipital parietal and temporal bones severely compressing the cerebellum and the right occipital lobe. Histologically it was characterised by the presence of multiple lobules containing osteoid or cartilage and separated by fibrous septae features typical of MTB. Lung metastases were evident. To our knowledge this is the first report of an MTB causing both severe cerebral and cerebellar compression and the second detailed report of an MTB of the occipital bone. MTB should be included in the differential diagnosis of bone tumours as well as in cases with central vestibular disease. Keywords dog metastases multilobular tumour osseous neoplasms skull Multilobular tumour of bone MTB is an uncommon tumour that typically affects the canine skull usually presenting as a firm circumscribed and generally slow-growing bone tumour in older dogs from medium or large breeds. Its biological behaviour may range from benign to malignant with the potential to invade metastasise and recur 16 . Histologically it is characterised by the dominant presence of multiple osteoid- or cartilagecontaining lobules that are separated by fibrous septae 15 . Although most .