tailieunhanh - Báo cáo y học: "An illuminated view of molecular biology"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: An illuminated view of molecular biology Yoseph Barash1,2* and Xinchen Wang2. | Barash and Wang Genome Biology 2010 11 307 http 2010 11 8 307 w Genome Biology MEETING REPORT L An illuminated view of molecular biology Yoseph Barash - 2 and Xinchen Wang2 Abstract A report on the 8th Annual International Conference on Intelligent Systems for Molecular Biology ISMB and the 7th Special Interest Group meeting on Alternative Splicing Boston USA- 9-13 July 20 0. Everything is Illuminated Liev Schreiber s 2005 directorial debut is a charming offbeat movie about a young man on a self-driven quest in a foreign land. Through his journey he finds connections between past and present and between things that initially appear completely unrelated. Both the title and the unifying theme of the movie match current trends and advances in molecular biology well. Like the character in the film researchers meticulously collect information using newly developed high-throughput and high-resolution technologies. And as they work to make sense of these new findings unifying themes begin to emerge. At the recent International Conference on Intelligent Systems for Molecular Biology and the associated Special Interest Group meeting on Alternative Splicing in Boston attendees were treated to talks covering diverse topics that when taken together offered a glimpse of the interconnectedness of traditionally separate fields in molecular biology and the ever-improving tools available to study them. Here we present a few of the highlights of the meetings. A unified view of the transcriptome At the level of the transcriptome evidence is accumulating about the physical and regulatory coupling between RNA splicing and nucleosome positioning histone modifications and non-coding RNAs. Nature does not seem to follow the human-contrived definitions that separate biological processes or research fields and building a unified model of the transcriptome requires combining Correspondence yoseph@ Biomedical Engineering Department of Electrical