tailieunhanh - Báo cáo y học: " Immunity and other defenses in pea aphids, Acyrthosiphon pisum"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Immunity and other defenses in pea aphids, Acyrthosiphon pisum. | Gerardo et al. Genome Biology 2010 11 R21 http 2010 11 2 R21 w Genome Biology RESEARCH Open Access Immunity and other defenses in pea aphids Acyrthosiphon pisum l I I r I z h I m ZM zzd z 1D z Z A ii i r i r rylf 2 V r I I z A r Z I m Z 3 4 I_I Z t z A m I SV 5C hh D srri Pi z I I 1 h z z t V zd Z z r 6 Nicole M Gerardo Boran AltinciceK Caroline Anselme nagop Atamian Bern M Barribeau Martin oe Vos E I i -7- I .Z it p I n I I z--U-C Im r Dl Cr S r8 I z p ni s I zd z3 9 h ỉ I I z- i zd p s V . I rn 13 A zd z I 71 7 I_I Z XZ I zd I3 I ỉ r i z I I p I 12 I z r p I 5 Elizabeth J Duncan Jay D Evans loni Gabaldon Murao Ghanim Aoeiaziz neooi Isgouhi Kaioshian 13 1 Amparo Latorre Andres Moya Atsushi NaKabachi Benjamin J Parker Vincente Pérez-Brocal Miguel Pignatelli11 12 Yvan Rahbé3 John S Ramsey6 Chelsea J Spragg1 Javier Tamames11 12 Daniel Tamarit11 12 Cecilia TamborinOeguy14 15 Caroline Vincent-Monegat3 Andreas VilcinsKas2 Abstract Background Recent genomic analyses of arthropod defense mechanisms suggest conservation of Key elements underlying responses to pathogens parasites and stresses. At the center of pathogen-induced immune responses are signaling pathways triggered by the recognition of fungal bacterial and viral signatures. These pathways result in the production of response molecules such as antimicrobial peptides and lysozymes which degrade or destroy invaders. Using the recently sequenced genome of the pea aphid Acyrthosiphon pisum we conducted the first extensive annotation of the immune and stress gene repertoire of a hemipterous insect which is phylogenetically distantly related to previously characterized insects models. Results Strikingly pea aphids appear to be missing genes present in insect genomes characterized to date and thought critical for recognition signaling and Killing of microbes. In line with results of gene annotation experimental analyses designed to characterize immune response through the isolation