tailieunhanh - Báo cáo khoa học: "All blood, No stool: enterohemorrhagic Escherichia coli O157:H7 infection"

Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: All blood, No stool: enterohemorrhagic Escherichia coli O157:H7 infection | J. Vet. Sci. 2008 9 3 219-231 JOURNAL OF Review Veterinary Science All blood No stool enterohemorrhagic Escherichia coli O157 H7 infection Jang W. Yoon1 1 Carolyn J. Hovde2 Division of Molecular and Life Science Hanyang University Ansan 426-791 Korea 2Department of Microbiology Molecular Biology and Biochemistry University of Idaho Moscow ID 83844-3052 USA Enterohemorrhagic Escherichia coli serotype O157 H7 is a pathotype of diarrheagenic E. coli that produces one or more Shiga toxins forms a characteristic histopathology described as attaching and effacing lesions and possesses the large virulence plasmid pO157. The bacterium is recognized worldwide especially in developed countries as an emerging food-borne bacterial pathogen which causes disease in humans and in some animals. Healthy cattle are the principal and natural reservoir of E. coli O157 H7 and most disease outbreaks are therefore due to consumption of fecally contaminated bovine foods or dairy products. In this review we provide a general overview of E. coli O157 H7 infection especially focusing on the bacterial characteristics rather than on the host responses during infection. Keywords enterohemorrhagic Escherichia coli O157 H7 Escherichia coli Escherichia E. coli was first described in 1885 by Theodore Escherich as a pure culture of slim occasionally slightly curved and short rods ranging in size from 1-5 pm in length and pm in thickness 9 . As a part of the normal gut microflora this microorganism colonizes the gastrointestinal tract of warm-blooded animals and humans within a few hours after birth and plays an important role in maintaining gut physiology 9 35 . However some E. coli strains have acquired specific virulence factors by means of mobile genetic elements such as plasmids transposons bacteriophages and pathogenicity islands and have evolved into pathogenic E. Corresponding author Tel 1-208-885-5906 Fax 1-208-885-6518 E-mail cbohach@ Present address Oriental Medical .