tailieunhanh - What Lung Cancer Patients Need to Know About Bone Health: A Publication of The Bone and Cancer Foundation

Treatments that take into account the physics of can- cer cells and tumours could, however, offer radically new approaches, especially when combined with nano- technology. As far as the NCI initiative is concerned, it is mainly focused on pure research and is not seeking to develop new treatments, although one group at the Houston Physical Sciences-Oncology Center in Texas, led by Mauro Ferrari, is trying to get gold nanoparticles inside cancer cells to see if microwaves can literally cook the cells to death. The holy grail, for me at least, would be to discover a simple on–off switch for cancer that could be thrown by manipulating a well-understood parameter such as temperature. | What Lung Cancer Patients Need to Know About Bone Health a Publication Of The Bone and Cancer Foundation Contents This publication provides important information about the relationship between lung cancer and bone health. HOW bone Works page 2 . What lung Cancer can do to bone page 2 . Treating bone Affected by lung Cancer page 3 . hypercalcemia page 5 . Glossary page 6 . 1 How Bone Works To understand the impact lung cancer can have on bone it is helpful for patients to understand what the skeleton does. Bone is an active tissue with many functions. In addition to supporting the body it serves as a storehouse for calcium and phosphorus essential minerals needed throughout the body. Bone also contains marrow the tissue that makes blood cells. Normal bone constantly undergoes a process called remodeling. During the bone remodeling process Bone cells called osteoclasts break down and remove resorb bone. Bone cells called osteoblasts make and deposit new bone at the site of bone removal. Hormones and other substances produced by the body regulate the way these bone cells are formed and how they work. What Lung Cancer Can Do to Bone Radiation chemotherapy and steroids are treatments for lung cancer that can weaken bone. To determine whether the skeleton is being affected by lung cancer treatment many doctors recommend that patients be given screening tests to measure their bone density before during and after cancer treatment Approximately 30 to 40 percent of people with lung cancer will have their cancer spread or metastasize to bone. When lung cancer metastasizes tumor cells from the original cancer break off and travel through the blood stream to a new location where they grow and multiply. Although lung cancer can spread to any part of the skeleton tumor cells most often affect the bones that have the greatest blood supply. These include the ends of the arms and legs nearest the torso the pelvis the ribs and the spine. When lung cancer spreads to bone several .