tailieunhanh - Báo cáo khoa học: "Idiopathic intranuclear inclusion bodies in the renal tubular epithelia of Japanese quail (Coturnix coturnix japonica)"

Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: Idiopathic intranuclear inclusion bodies in the renal tubular epithelia of Japanese quail (Coturnix coturnix japonica) | J. Vet. Sci. 2005 6 1 75-76 JOURNAL OF Short Communication Veterinary Science Idiopathic intranuclear inclusion bodies in the renal tubular epithelia of Japanese quail Coturnix coturnix japonica Seung-Hyeok Seok Jong-Hwan Park Sun-A Cho Jae-Hak Park Department of Laboratory Animal Medicine College of Veterinary Medicine Seoul National University Seoul 151-742 Korea We report idiopathic intranuclear inclusion bodies in the renal tubular epithelia of two cases of among the 960 Japanese quail Coturnix coturnix japonica in the course of the acute oral toxicity and dietary toxicity test. Basophilic inclusion bodies were seen only in the nuclei of renal tubular epithelia. We could not classify our case into any adenovirus infection by clinical signs and lesions. The inclusion bodies were only identified as adenovirus-like particles based upon the electronmicroscopical features. Key words Adenovirus-like particles Japanese quail Coturnix coturnix japonica Inclusion body Intranuclear inclusion bodies in the renal epithelium of birds are usually caused by viruses inclusion body hepatitis virus avian adenovirus-1 or haemorrhagic enteritis virus avian adenovirus-2 5 7 . Here we found two cases of idiopathic intranuclear inclusion bodies in the renal tubular epithelia among the 960 Japanese quail Coturnix coturnix japonica in the course of the acute oral toxicity and dietary toxicity test. Althouh we could not classify present case into virus infections by clinical signs and lesions we report the characteristic features of the idiopathic intranuclear inclusion bodies. Nine hundred and sixty male and female 6-week-old Japanese quail Coturnix coturnix japonica weighing 130150 g were obtained from a local supplier Suwon-Ezo Suwon Korea . All animal experiments were performed under protocols approved by Institutional Animal Care and Use Committee of Seoul National University. The quail were kept at room temperature of 22 2oC and 55 10 relative humidity and received 8 16 h of light