tailieunhanh - Báo cáo khoa hoc:" Miguel of genetic markers in conservation programmes use"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học thế giới đề tài: Miguel of genetic markers in conservation programmes use | Genet. Sei. Evol. 31 1999 255-261 255 Inra Elsevier Paris Note Optimal use of genetic markers in conservation programmes Miguel Toro Luis Silió Jaime Rodriganez Carmen Rodríguez Jesus Fernandez Departamento de Mejora Genética y Biotecnología INIA Ctra. de La Coruna km 7 28040 Madrid Spain Received 24 November 1998 accepted 26 March 1999 Abstract Monte Carlo simulations were carried out in order to study the benefits of using molecular markers to minimize the homozygosity by descent in a conservation scheme of the Iberian pig. A selection criterion is introduced the overall expected heterozygosity of the group of selected individuals. The method to implement this criterion depends on the type of information available. In the absence of molecular information breeding animals are chosen that minimize the average group coancestry calculated from pedigree. If complete molecular information is known the average group coancestry is calculated either from markers alone or by combining pedigree and genotypes with the markers. When a limited number of markers and alleles per marker are considered the optimal criterion is the average group coancestry based on markers. Other alternatives such as optimal within-family selection and frequencydependent selection are also analysed. Inra Elsevier Paris conservation genetics molecular markers average coancestry Resume - utilisation optimale des marqueurs génétiques dans les programmes de conservation. Des simulations Monte Carlo ont été effectuees pour étudier 1 intérêt de 1 utilisation des marqueurs moléculaires pour minimiser le taux d homozygotie par replication mendélienne dans un schema de conservation du pore ibérique. Un critère de selection a été introduit le taux global espéré d heterozygotie du groupe des individus sélectionnés. La methode pour appliquer ce critère depend du type d information disponible. A defaut d information moléculaire on choisit les animaux reproducteurs qui minimisent la parenté moyenne du groupe .