tailieunhanh - Báo cáo khoa học: "Effects of Combination Dietary Conjugated Linoleic Acid with Vitamin A (Retinol) and Selenium on the Response of the Immunoglobulin Productivity in Mice"

Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: Effects of Combination Dietary Conjugated Linoleic Acid with Vitamin A (Retinol) and Selenium on the Response of the Immunoglobulin Productivity in Mice | J. Vet. Sci. 2003 4 1 103-108 JOURNAL OF Veterinary Science Effects of Combination Dietary Conjugated Linoleic Acid with Vitamin A Retinol and Selenium on the Response of the Immunoglobulin Production in Mice Jin-young Kim and Byung-hyun Chung College of Veterinary Medicine Konkuk University Seoul 143-701 Korea Received February 26 2003 Accept March 30 2003 Abstract The dietary effect of conjugated linoleic acid CLA on the response of the immunoglobulin serum and tissue production in Balb C mice was examined at three doses 0 control and The combin ation effects of CLA with vitam in ADE or selenium also were investigated. CLA at increased serum immunoglobulin A G mesenteric lymp node MHN and gut luminal IgA secretory IgA levels. How ever CLA decreased SIgG slightly. CLA both alone and com bined with vitam in ADE and selenium did not affect serum IgE. The levels of immunoglobulin concentration in the CLA group were higher than those in CLA group. The level of serum IgG in CLA com bined with selenium was maintained at the same level as that of control. It is considered that ove r-doses of CLA even depressed the production of immunoglobulin but selenium and or vitamin inhibited this activity to a certain extent. In this study dietary CLA increased immunoglobulin production in a dose-dependent m anner. Vitam in ADE and S elenium com bined with CLA also increased the immunoglobulin production response except serum IgE. Key Words immunoglobulin conjugated linoleic acid vitamin ADE selenium Introduction Conjugated linoleic acid CLA is a derivative of a fatty acid lin oleic a cid which is found in var iou s ruminant -derived foodstuffs such as milk cheese and yogurt 7 24 . It has been reported that CLA decr ea ses carcinogenesis 14 18 19 20 21 38 diabetes 16 and atherosclerosis 7 41 . Corresponding Author Byung-hyun Chung College of Veterinary Medicine Konkuk University Seoul 143-701 Korea Tel 82-02-450-3717 E-mail .