tailieunhanh - Báo cáo sinh học: "Pox proteomics: mass spectrometry analysis and identification of Vaccinia virion proteins"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Pox proteomics: mass spectrometry analysis and identification of Vaccinia virion proteins | BioMed Central Virology Journal Open Access Pox proteomics mass spectrometry analysis and identification of Vaccinia virion proteins Jennifer D Yoder1 Tsefang S Chen1 Cliff R Gagnier1 Srilakshmi Vemulapalli2 Claudia S Maier3 and Dennis E Hruby 1 Address 1Oregon State University Department of Microbiology 220 Nash Hall Corvallis OR 97331-3804 USA 2Oregon State University Applied Biotechnology Program 2082 Cordley Hall Corvallis OR 97331-8530 USA and 3Oregon State University Department of Chemistry 153 Gilbert Hall Corvallis OR 97331-4003 UsA Email Jennifer D Yoder - yoderj@ Tsefang S Chen - Cliff R Gagnier - gagnierc@ Srilakshmi Vemulapalli - vemulasr@ Claudia S Maier - Dennis E Hruby - hrubyd@ Corresponding author Published 01 March 2006 Received 16 February 2006 Accepted 01 March 2006 Virology Journal 2006 3 10 doi l 743-422X-3-10 This article is available from http content 3 1 10 2006 Yoder et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Although many vaccinia virus proteins have been identified and studied in detail only a few studies have attempted a comprehensive survey of the protein composition of the vaccinia virion. These projects have identified the major proteins of the vaccinia virion but little has been accomplished to identify the unknown or less abundant proteins. Obtaining a detailed knowledge of the viral proteome of vaccinia virus will be important for advancing our understanding of orthopoxvirus biology and should facilitate the development of effective .