tailieunhanh - Báo cáo hóa học: " An Effective Amperometric Biosensor Based on Gold Nanoelectrode Arrays"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: An Effective Amperometric Biosensor Based on Gold Nanoelectrode Arrays | Nanoscale Res Lett 2009 4 210-215 DOI S11671-008-9227-0 NANO EXPRESS An Effective Amperometric Biosensor Based on Gold Nanoelectrode Arrays Yanyan Liu Yingchun Zhu Yi Zeng Fangfang Xu Received 21 October 2008 Accepted 25 November 2008 Published online 9 December 2008 to the authors 2008 Abstract A sensitive amperometric biosensor based on gold nanoelectrode array NEA was investigated. The gold nanoelectrode array was fabricated by template-assisted electrodeposition on general electrodes which shows an ordered well-defined 3D structure of nanowires. The sensitivity of the gold NEA to hydrogen peroxide is 37 times higher than that of the conventional electrode. The linear range of the platinum NEA toward H2O2 is from 1 X 10-6 to 1 X 10-2 M covering four orders of magnitudes with detection limit of 1 X 10-7 M and a single noise ratio S N of four. The enzyme electrode exhibits an excellent response performance to glucose with linear range from 1X 10-5 to 1 X 10 M and a fast response time within 8 s. The Michaelis-Menten constant km and the maximum current density imax of the enzyme electrode were mM and A cm-2 respectively. This special nanoelectrode may find potential application in other biosensors based on amperometric signals. Keywords Gold nanowires Nanoelectrode arrays Amperometric biosensor Y. Liu Key Lab Special Functional Materials Henan University Kaifeng 475004 People s Republic of China Y. Liu Y. Zhu Y. Zeng F. Xu Chinese Academy of Sciences Key Lab of Inorganic Coating Shanghai Institute of Ceramics Dingxi Road Shanghai 200050 People s Republic of China e-mail yzhu@ yingchunzhu@ Introduction Biosensors based on electrochemistry are now attracting considerable attention as potential successors to a wide range of analytical techniques due to their unique properties of specificity 1-3 . The key aspect of an electrochemical biosensor is the generation or modulation of electrical current in an electronic circuit .