tailieunhanh - báo cáo hóa học: "Patient-reported benefit of ReSTOR® multi-focal intraocular lenses after cataract surgery: Results of Principal Component Analysis on clinical trial data"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài:Patient-reported benefit of ReSTOR® multi-focal intraocular lenses after cataract surgery: Results of Principal Component Analysis on clinical trial data | BioMed Central Health and Quality of Life Outcomes Research Patient-reported benefit of ReSTOR multi-focal intraocular lenses after cataract surgery Results of Principal Component Analysis on clinical trial data Gilles Berdeaux 1 2 Muriel Viala3 Aude Roborel de Climens3 and Benoit Arnould3 Address 1Alcon France Rueil-Malmaison France 2Conservatoire National des Arts et Metiers Paris France and 3Mapi Values Lyon France Email Gilles Berdeaux - Muriel Viala - MViala@ Aude Roborel de Climens - aroborel@ Benoit Arnould - barnould@ Corresponding author Open Access Published 24 January 2008 Received 20 August 2007 Health and Quality of Life Outcomes 2008 6 10 doi 1477-7525-6-10 Accepted 24 January 2008 This article is available from http content 6 1 10 2008 Berdeaux et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Restoration of functional distance and near vision independently of additional correction remains a goal for cataract surgery. ReSTOR a new multi-focal intraocular lens IOL addresses this issue with an improvement in both distance and near vision often without need for glasses. This analysis attempted to discuss the patient-reported benefit of ReSTOR using a full but organised representation of data. Methods Two non-randomised open-label clinical trials conducted in Europe and the United-States were conducted to compare the efficacy of ReSTOR to AcrySof mono-focal IOLs. A total of 710 patients in need of bilateral cataract extraction were included in the pooled study. The TyPE a patient questionnaire was fully completed by 672 of them before and after each eye surgery. The TyPE composed of 67 items measuring overall visual .