tailieunhanh - Báo cáo khoa học: "Effects of Electroacupuncture on Minimum Alveolar Concentration of Isoflurane and Cardiovascular System in Isoflurane Anesthetized Dogs"

Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: Effects of Electroacupuncture on Minimum Alveolar Concentration of Isoflurane and Cardiovascular System in Isoflurane Anesthetized Dogs | J. Vet. Sci. 2002 3 3 193-201 JOURNAL OF Veterinary Science Effects of Electroacupuncture on Minimum Alveolar Concentration of Isoflurane and Cardiovascular System in Isoflurane Anesthetized Dogs Seong-Mok Jeong College of Veterinary Medicine Seoul National University San 56-1 Shillim 9-dong Kwanak-gu Seoul 151-742 Korea Received July 12 2002 Accepted September 2 2002 Abstract The effects of electroacupuncture EA on the minimum alveolar concentration MAC and on the cardiovascular system were evaluated with dogs under isoflurane anesthesia. Eight healthy male beagles were randomly assigned to six study groups five heads group with washout intervals of 7 31 days between experiments for recovery and anesthetic clearance. MAC of isoflurane and cardiovascular parameters were determined after EA at nonacupoint and and at acupoints LI-4 SP-6 ST-36 and TH-8. Electroacupuncture for 30 minutes at LI-4 SP-6 ST-36 and TH-8 acupoints lowered the MAC of isoflurane by and respectively p . However electrical stimulation of nonacupoint did not induce a significant change in MAC of isoflurane. In the cardiovascular system the ST-36 group did not induce any significant change in cardiovascular parameters. In the TH-8 group the mean and diastolic arterial pressure and the systemic vascular resistance were decreased. In the LI-4 group cardiac output and cardiac index decreased after EA. These results indicate that EA at LI-4 SP-6 and ST-36 have advantages in isoflurane anesthesia in terms of reducing the dose of anesthetics and minimizing cardiovascular side effects. Key words dog electroacupuncture isoflurane minimum alveolar concentration cardiovascular system Introduction Isoflurane was developed in 1965 and approved in the late 1970 s in many countries. It has been widely used in veterinary and human practice because of its chemical stability and minimal side effects. However isoflurane has Corresponding author Seong-Mok Jeong DVM PhD .